Just mere life is not victory, just mere death is not defeat.

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GSW, Explained by a Doctor

I will not post many links to other websites (or blogs/etc) unless highlighting a product, linking a description or coming across something I believe is technically accurate enough to share.  This doctor in the video does a good job at explaining real world GSWs (gun shot wounds).  His observations and technical descriptions are consistent with what I have personally seen/experienced on duty.  The beginning is some explanation, the middle is the good stuff and the end is more for the med. students than anyone else.  Its about 34 minutes long and the quality is not that great (probably a phone camera), but its all good info.

I will update this post later with my personal opinions on this topic.

Personal Opinion:

So after watching this video you probably want to go out and buy a .45 or something in the .44 / .454 area and while that may be a great idea, think objectively about what the doctor in the video said.  "Structure" destruction is what you want, a lot of it and mainly the main portions of the important structures:

So you can see there are a lot of places for you to put your bullets and this is not the limit.  The red box outlines the main area of shooting that you want to do, aside from the head.  It is also the main part of your body you want to put any sort of armor on top of.  The heart, including the aortic arch is definitely something you want to try to hit in order to set off a timer. 

The doctor made it pretty clear that most people die because of bleeding out, not because of the sheer destructive power of a pistol caliber.  Pistol calibers are extremely ineffective at stopping a human quickly and effectively.  Shooting someone in the head may not stop them immediately, shooting them in the chest may not stop them immediately so is a bigger caliber the answer? Maybe.  I would say that any good pistol with modern ammunition in the hands of a person who is able to repetitively hit the area which will help stop the thread is the best for the job.  If you are a person who is able to put .45ACP rounds within inches of each other in close proximity to an important "structure" then go for it.  Chances are however that a 9mm will probably work just as well, and most people I have shot with in classes can do this with a 9mm better than a .45ACP.  Accurate shots on target, in the correct locations will do the best job and that is what we need to practice and strive for.